Statistical processing of the data for the presence of Q fever in human population in Western Macedonia

MIJE REÇI^1*, LEONORA QOKU²

¹Faculty of Natural Sciences and Math, Study Program of Biology, University of Tetova, Tetovo, Macedonia,

²Faculty of Natural Sciences and Math, Study Program of Biology, University of Tetova, Tetovo, Macedonia,

*Corresponding author e-mail: mije.reci @unite.edu.mk

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Abstract

Q fever is an acute and rarely chronic, zoonotic disease. It is caused by Coxiella burnetii, an obligate intracellular, pleomorphic coccobacillus. It survives unfavourable conditions in the form of endospores and is extremely resistant to environmental effects. People are usually infected by inhaling the infected aerosol. The aim of study was to examine the frequence of Q fever in the human population in Western Macedonia and determining the statistical trend with descriptive and conclusive statistical methods. The serological test was conducted using the ELISA test kit. The serum isolated from the blood was kept at -30°C until testing. The sera were properly diluted based on therespective protocol using purified antigen of C. Burnetii. A total of 520 serums were checked of all ages from people with different epidemiological conditions, of which 114 resulted positive, with positivity rate of about 21.90%.The standard deviation of the infected population in general is 8.53, where in the female gender is higher than the masculine gender, while the age group of the two sexes the standard deviation ranges from 0.84 to 4.98. The statistical analysis of the data results, prove that there is a connection and similarity among the samples from five regions in terms of the spread of the Q fever infection inhuman population, this is proven by the credibility boundaries with the Kloper-Pirson method. The frequency 78% negative per sample 520 is gained within the median limits from 74% to 86% of the sample.

Keywords: Zoonotic disease, human population, infection, serological test, regions.